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Concurrent disorders
 
Concurrent disorders are other types of disorders that occur with thryoid disorders more frequently than in the general public
 
There is a going body of evidence on the co-occurrence of thyroid disorders and other autoimmune disorders.  One study in 2007 reported a prevalence rate of 60% for rheumatic disorders and 15% for other autoimmune disorders among patients with autoimmune thyroid disorders.
 
The common concurrent disorders are:
  • Rheumatic disorders
  • Other autoimmune disorders
  • Mixed connective tissue disease
  • Sjögren's syndrome  
  • Systemic lupus erythematosus
  • rheumatoid arthritis
  • multiple scleroses
  • systemic sclerosis
  • diabetes
  • c
    eliac disease
  • myasthenia gravis
  • fibromylagia

One possible explanation for dissatisfaction with treatment is an undetected concurrent disorder.  If the prevalence rates are generalizable from these studies, then it would seem reasonable to implement routine screening for concurrent disorders for anyone with a thyroid disorder as was suggested by Biro.


[1]  Soy, Mehmet; Guldiken, Sibel; Arikan, Ender; Altun, Betul; Tugrul, Armagan: Frequency of rheumatic diseases in patients with autoimmune thyroid disease Rheumatology International, Volume 27, Number 6, April 2007 , pp. 575-577(3)

[2] Biró E, Szekanecz Z, Czirják L, Dankó K, Kiss E, Szabó NA, Szucs G, Zeher M, Bodolay E, Szegedi G, Bakó G. Association of systemic and thyroid autoimmune diseases. Clin Rheumatol. 2006 Mar;25(2):240-5. Epub 2005 Oct 25.

[3] Sloka, JS, Pryse-WEM Phillips M Stefanelli  and C Joyce  Co-occurrence of autoimmune thyroid disease in a multiple sclerosis cohort Journal of Autoimmune Diseases (Newfoundland).The Canadian Journal of Neurological Sciences Volume 32, Number 1 / February 2005:  37 - 42

[4] Jara LJ, Navarro C, Brito-Zerón Mdel P, García-Carrasco M, Escárcega RO, Ramos-Casals M. Thyroid disease in Sjögren's syndrome. Clin Rheumatol. 2007 Oct;26(10):1601-6. Epub 2007 Jun 9. Review.

[5] Caramaschi P, Biasi D, Volpe A, Carletto A, Cecchetto M, Bambara LM. Coexistence of systemic sclerosis with other autoimmune diseases. Rheumatol Int. 2007 Feb;27(4):407-10. Epub 2006 Sep 19.

[6] Alvarez-Marfany M, Roman SH, Drexler AJ, Robertson C, Stagnaro-Green A. Long-term prospective study of postpartum thyroid dysfunction in women with insulin dependent diabetes mellitus. J Clin Endocrinol Metab. 1994;79:10-16.

[7] Spadaccino AC, Basso D, Chiarelli S, Albergoni MP, D'Odorico A, Plebani M, Pedini B, Lazzarotto F, Betterle C. Celiac disease in North Italian patients with autoimmune thyroid diseases. Autoimmunity. 2008 Feb;41(1):116-21.

[8] Cuoco L, Certo M, Jorizzo RA, De Vitis I, Tursi A, Papa A, De Marinis L, Fedeli P, Fedeli G, Gasbarrini G. Prevalence and early diagnosis of coeliac disease in autoimmune thyroid disorders. J Gastroenterol Hepatol. 1999 May;31(4):283-7.

[9]  Association between thyroid autoimmunity and fibromyalgic disease severity.

      Bazzichi L, Rossi A, Giuliano T, De Feo F, Giacomelli C, Consensi A,  

      Ciapparelli A, Consoli G, Dell'osso L, Bombardieri S.

      Clin Rheumatol. 2007 Dec;26(12):2115-20.